DIY & Crafts ruling
Can drywall compound go down the drain?
It hardens, settles or coats. Your drain would prefer none of those verbs.
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Sink or drainNo
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Garbage disposalNo
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ToiletNo
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Septic systemNo
01
Why the pipe objects
Joint compound contains fine solids that settle into a dense layer and can dry hard inside plumbing.
02
Do this instead
Scrape tools into a container, let residue dry and dispose of it according to local construction-waste guidance.
03
Already did it?
Stop running water; more water may carry the material deeper. Scoop or wipe up what remains and call a plumber if a meaningful amount entered the line.